結論:目前著重於anti-muscarinics治療老年男性夜尿之文獻相當有限,因此並無足夠的證據支持anti-muscarinics可改善老年男性之夜尿問題。且Weiss等學者認為較年輕之男性(<50歲)之夜尿原因多半來自減少的夜間膀胱容量(reduced night bladder capacity);而老年男性(>70歲)則多半歸因於夜間多尿症(nocturnal polyuria,NP)[6]。
定時利尿劑治療(Timed diuretic therapy) 針對於下半身水腫所導致之的夜尿症,適時地在下午給予病患利尿劑(bumetanide或是furosemide,睡前6至10小時),使其在入睡前能發揮利尿作用,對於夜尿也有幫助(Level 2 evidence, Grade C recommendation)[7]。
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